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PUBLICATIONS
Taylor,
R. E. "Tedanolide and the Evolution of Polyketide Inhibitors of
Eukaryotic Protein Synthesis" Nat.
Prod. Res. 2008, in press.
Daly,
E., Taylor, R. E "“Entropy and Enthalpy in the Activity of
Tubulin-based Antimitotic Agents” Curr.
Chem. Biol. 2008, in
press.
Kartika,
R.; Frein, J. D.; Taylor, R. E. "Electrophilone-Induced Ether Transfer:
Stereoselective Synthesis of 2,6-Disubstituted-3,4-Dihydropyrans" J. Org. Chem. 2008, in press.
Huzil,
J. T.; Chik, J. K.; Slysz, G. W.; Freedman, H.; Tuszynski, J.;
Taylor, R. E.; Sackett, D. L.; Schriemer, D. C. “A Unique Mode of
Microtubule Stabilization Induced by Peloruside A” J. Mol. Biol. 2008, 378, 1016-1030.
Young,
J.; Taylor, R. E. “Evolution of Polyketides: Post-PKS Processing in the
Formation of Spiroketals” Nat. Prod.
Rep. 2008, in press.
Taylor,
R. E.; Zhao, Z.; Wünsch, S. “Synthetic Efforts Towards Peloruside
A” Comptes Rendus de
l'Académie des Sciences - CHIMIE 2008, in press.
Kartika,
R.; Taylor, R. E. "Electrophile-Induced Ether Transfer:
An Expedient Route to 2-Cyano-tetrahydropyrans" Heterocycles 2007, 74, 447-459.
Kartika,
R.; Taylor, R. E. "Electrophile-Induced Ether Transfer:
Stereoselective Synthesis of 2,4,6-Trisubstituted Tetrahydropyrans" Angew. Chem. Int. Ed. 2007, 46, 6874-6877.
Taylor,
R. E.; Diene, C. R.; Daly, E. M. “46.11 Synthesis of 1,3-Dienes by
Isomerization of Unconjugated Dienes, Allenes, and Alkynes” in Houben-Weyl Science of Synthesis;
V. H. Rawal and S. A. Kozmin, Eds.; G. Thieme Verlag, Stuttgart, 2008, Vol. 46.
Daly,
E. M.; Taylor, R. E. “Recent
Applications of the Nozaki-Hiyama Kishi Reaction in Natural Product
Synthesis” Chemtracts 2007, 20, 1-8.
Tung,
J. C.; Chen, W.; Taylor, R. E.; Fields, S. C.; Dent III, W. H.; Green,
F. R. "Toward the Synthesis of the Cornexistins" Synthesis 2007, 2388-2396.
Kartika, R., Taylor, R. E. “An
Exhaustive Hydrogenation Strategy to Bicyclic Alkaloids” Chemtracts 2006, 19, 385-390.
Melancon,
B. J.; Perl, N. R.; Taylor, R. E. "Competitive Cationic Pathways and
the Asymmetric Synthesis of Aryl-Substituted Cyclopropanes" Org Lett. 2007, 9, 1425-1428.
Liu,
K.; Taylor, R. E.; Kartika, R. "Electrophile-Induced Ether Transfer: A
New Approach to Polyketide Structural Units" Org. Lett. 2006, 8, 5393-5395.
Hines,
J.; Roy, M.; Cheng, H.; Agapakis, C. M.; Taylor, R. E.; Crews, C.
M. “Myriaporone 3/4 SAR Studies Reveal a Novel Pharmacophore Targeting
Eukaryotic Protein Synthesis” Molecular
Biosystems 2006, 2, 371-379. Highlighted on the cover.
Taylor, R. E.; Fleming, K.
N.; Hearn, B. R. "Total Synthesis of Myriaporones 1, 3, and 4" in
Strategies and Tactics in Organic Synthesis" M. Harmata, Ed., Elsevier,
Amsterdam, 2005, pp. 246-268.
Paquette, W.
D.; Taylor,
R. E. "Conformationally-Biased Macrocyclizations" Chemtracts 2005, 18,
584.
Jin, M.; Taylor, R. E.
"The Total Synthesis of (+)-Peloruside A" Org. Lett . 2005,
7, 1303-1305.
Risatti, C. A.; Taylor, R.
E. "Asymmetric Synthesis of Cyclopropanes via Aldehyde Homologation" Angew. Chem. Int. Ed. 2004,
43, 6671-6672.
Suckow, M. A.; Gutierrez,
L. S.; Risatti, C. A.; Wolter, W. R.; Taylor, R. E.; Pollard, M.;
Navarri, R. M.; Castellino, F. J.; Paoni, N. F. “The
Anti-ischemia Agent Ranolazine Promotes the Development of Intestinal
Tumors in APC(Min/+) Mice” Cancer
Lett. 2004, 209, 165-169.
Fleming, K. N.; Taylor, R.
E. "Total Synthesis and Structural Assignment of Myriaporones 1, 3, and
4" Angew. Chem. Int. Ed. 2004,
43, 1728-1730.
Paquette, W. D.; Taylor,
R. E. "Enantioselective Preparation of the C1-C11 Fragment of
Apoptolidin" Org. Lett. 2004,
6, 103.
Taylor, R. E.; Jin, M.
"Towards the Total Synthesis of Peloruside A; Enantioselective
Preparation of the C8-C19 Region" Org.
Lett. 2003, 5, 4959.
Risatti, C. A.; Taylor, R.
E. "Biomimetic Synthesis of Polycyclic Natural Products from
Polyolefinic Precursors" Chemtracts 2004,
17, 83-91.
Taylor, R. E.; Chen, Y.;
Galvin, G. M.; Pabba, P. "Conformation-Activity Relationships in
Polyketide Natural Products: Towards the Biologically Active
Conformation of Epothilone" Organic
and Biomolecular Chemistry 2004, 2, 127.
Taylor, R. E.;
Engelhardt, F. C.; Schmitt, M. J. "Biosynthetic Inspirations:
Cationic Approaches to Cyclopropane Formation" Tetrahedron 2003,
59, 5623-5634.
Vitale-Brown, A. Taylor,
R. E. "Lewis Acid-Induced Epoxide Rerrangement for Complex Molecule
Synthesis" Chemtracts 2003,
16, 254-258.
Taylor, R. E.; Risatti, C.
A.; Engelhardt, F. C.; Schmitt, M. J. "Cyclopropane Structural Units
from Homoaldol Adducts" Org. Lett . 2003,
5, 1377-1379.
Fumihiko
Yoshimura,
Alexey
Rivkin, Ana E. Gabarda, Ting-Chao Chou, Huajin Dong, George Sukenick,
Florence F. Morel, Richard E. Taylor, and Samuel J. Danishefsky
"Synthesis and Conformational Analysis of (E)-9,10-Dehydroepothilone B,
the Most Potent Epothilone Reported to Date: A Suggestive Linkage
Between Observations in the Chemistry and Biology of Epothilones." Angew. Chem. Int. Ed. 2003,
42, 2518-2521.
Yuan, H.;
Junker,
B.;
Helquist, P.; Taylor, R. E. "Synthesis of Anti-Angiogenic Isocoumarins"
Current Organic
Synthesis 2004,
1, 1.
Taylor, R. E.; Chen, Y.;
Beatty, A.; Myles, D. C.; Zhou, Y. "Conformation-activity Relationships
in Polyketide Natural Products. A New Perspective on the Rational
Design of Epothilone Analogues"
J. Am. Chem.
Soc. 2003,
125, 26. This work was
highlighted by a Science Concentrate in Chemical and Engineering
News, a University of Notre Dame Press Release, and a news
story on NPR (WVPE and " " WFYI).
Taylor, R. E.; Ciavarri,
J. P.; Hearn, B. R.; Engelhardt, F. C.; Schmitt, M. J.; Yuan, H.
"Synthetic Methods for Chemical Diversity Inspired by Natural
Products" in Natural Product Chemistry at the Turn of the Century , 2002, (eds. Rahman, Choudary, Khan;
Print Arts, Karachi) p. 89
Taylor, R. E.; Hearn, B.
R.; Ciavarri, J. C. "A Divergent Approach to Tedanolide and
Myriaporone: Completion of the carbon Skeleton of Myriaporone 1."
Org. Lett. 2002, 4, 2953.
Taylor, R. E. "The Organic
Chemist's Newswire" (journal review) Nature
2001, 413, 678-679.
Engelhardt, F. C.;
Schmitt, M. J.; Taylor, R. E. "Kinetically Controlled Cross-Metathesis
Reactions with High E-Selectivities" Org.
Lett. 2001, 3, 2209-2212.
Taylor, R. E.; Chen, Y.
"The Total Synthesis of Epothilone B" Org.
Lett. 2001, 3, 2221-2224.
Taylor, R. E.; Engelhardt,
F. C.; Schmitt, M. J.; Yuan, H. "Synthetic Methods for the Construction
of Structurally Diverse Cyclopropanes"
J. Am. Chem.
Soc. 2001,
123, 2964.
Taylor, R. E.; Schmitt, M.
J.; Yuan, H. "Structural Diversity Based on Cyclopropane Scaffolds" Org. Lett. 2000,
2, 601-603.
Taylor, R. E.; Engelhardt,
F. C.; Yuan, H. "Oligocyclopropanes from Cationic Intermediates" Org. Lett. 1999,
1, 1257-1260.
Taylor, R. E.; Ciavarri,
J. P. "2-Bromoallyl Acetate: A Useful Structural Unit for Sequential
Carbon-Carbon Bond Formation" Org.
Lett. 1999, 1, 467-470.
Taylor, R. E.; Zajicek, J.
"The Conformational Properties of Epothilone" J. Org. Chem. 1999,
64, 7224-7228.
Taylor, R. E.; Ciavarri,
J. C.; Hearn, B. R. "A Divergent Approach to Tedanolide and
Myriaporone: Enantioselective Preparation of the Common
Intermediate" Tetrahedron Lett. 1998,
39, 9361.
Taylor, R. E.; Galvin, G.
M.; Hilfiker, K. A.; Chen, Y. "A Formal Total Synthesis of Epothilone
A: Asymmetric Preparation of the C1-C6 and C7-C12 Fragments" J. Org. Chem. 1998,
63, 9580.
Patterson, S.; Smith, B.
D.; Taylor, R. E. "Tuning the Affinity of a Synthetic Sialic Acid
Receptor Using Combinatorial Chemistry" Tetrahedron Lett. 1998, 39, 3111.
Patterson, S.; Smith, B.
D.; Taylor, R. E. "Fluorescent Sensing of Ribonucleoside
5'-Triphosphate" Tetrahedron Lett. 1997,
38, 6323.
Taylor, R. E.; Ameriks, M.
K.; LaMarche, M. J. "A Novel Approach to Oligocyclopropane Structural
Units" Tetrahedron Lett. 1997,
38, 2057.
Taylor, R.
E.;
Haley,
J.
D. "Towards the Synthesis of Epothilone A. Enantioselective Preparation
of the Thiazole Sidechain and Macrocyclic Ring Closure" Tetrahedron Lett. 1997,
38, 2061.
Publications
with Paul Wender
Wender, P.
A.;
Taylor,
R.
E.; Taxol subgroup "The Pinene Path to Taxanes 5. Stereocontrolled
Synthesis of a Versatile Taxane Precursor" J. Am. Chem. Soc. 1997, 119, 2755.
Wender, P.
A.;
Taylor,
R.
E.; Taxol subgroup "The Pinene Path to Taxanes 6. A Concise Synthesis
of Taxol" J. Am. Chem. Soc. 1997,
119, 2757.
Wender,P.
A.;
Taylor,
R.
E.; Taxol subgroup "The Pinene Path to Taxanes: Genesis and Evolution
of a Synthesis Strategy" ACS Symposium Series 583, Taxane Anticancer
Agents: Basic Science and Current Status Ojima, I.; Georg, G. Ed.
American Chemical Society: Washington D. C., 1995, pp. 326-339.
Publications
with Art Schultz
Schultz, A.
G.;
Taylor,
R.
E. "Diastereoselective Enolate Alkylations. Asymmetric Syntheses of
3-Alkyl-3-carbomethoxy-2-exo-methylene- cyclohex-5-en-1-ones." J. Am. Chem. Soc. 1992,
114, 3937.
Schultz, A.
G.;
Taveras,
A. G.; Taylor, R. E.; Tham, F. S.; Kullnig, R. K. "Solid State
Photochemistry. Remarkable Effects of the Packing of Molecules in
Crystals on the Diastereoselectivity of the Intramolecular 2+2
Photocycloaddition of a 4-(3'-Butenyl) -2,5-cyclohexadien-1-one." J. Am. Chem. Soc. 1992,
114, 8725
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