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COURSE DESCRIPTION |
This graduate-level course takes a fluid mechanics approach to describe the human cardiovascular system and the intricate relations between hemodynamics and cardiovascular physiology/pathophysiology. Topics include cardiovascular physiology, blood rheology, human circulation biomechanics and fluid mechanics, biofluid mechanics modeling, and measurement techniques. By the end of this course, students will be able to:
- Describe the physiology, pathophysiology and anatomy of the cardiovascular system
- Describe the different models of blood flow in cardiovascular structures
- Identify and recognize the effects of blood flow on cardiovascular tissue physiology
- Describe the different measurement techniques implemented to measure blood flow in cardiovascular structures
- Apply this knowledge to solve clinical research problems
- Describe the physiology, pathophysiology and anatomy of the cardiovascular system
- Describe the different models of blood flow in cardiovascular structures
- Identify and recognize the effects of blood flow on cardiovascular tissue physiology
- Describe the different measurement techniques implemented to measure blood flow in cardiovascular structures
- Apply this knowledge to solve clinical research problems
The topics to be covered include:
1. Introduction
2. Cardiovascular physiology
3. Blood rheology
4. Human circulation biomechanics
5. Fluid-structure interaction modeling
6. Human circulation fluid mechanics
7. Measurement techniques
8. Analysis and management of cardiovascular disease
ANNOUNCEMENTS |
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| 4/23/12: | Flow measurement techniques slides posted |
| 4/19/12: | Solution of pulsatile flow in elastic tube (part 2) handout posted |
| 4/17/12: | Solution of pulsatile flow in elastic tube (part 1) handout posted Ch6. Womersley Solution (supplement) posted |
DOWNLOADS |
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| Syllabus (posted 1/09/12) |
Schedule (posted 1/09/12) |
PROJECT-SPECIFIC FILES |
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| Project outlines (posted 2/01/12) |
Assessment critera (posted 2/01/12) |
Steps to launch ADINA (posted 2/06/12) |
.cshrc file (posted 2/06/12) |
Example models (posted 2/06/12) |
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| Proposal template (posted 2/06/12) |
Literature review guidelines (posted 2/06/12) |
Example of project proposal with assessment (posted 2/20/12) |
Specific Aims |
Specific Aims (example 2) (posted 2/27/12) |
CHAPTER 1: INTRODUCTION |
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| Ch1. Introduction (posted 1/18/12) |
Index notation (posted 1/18/12) |
Index notation examples (posted 1/18/12) |
Equilibrium conditions (posted 1/18/12) |
Deformation analysis (posted 1/18/12) |
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| Analysis of thin-walled tubes (posted 1/24/12) |
Analysis of thick-walled tubes (posted 1/24/12) |
Fluid mechanics constitutive equations (posted 1/27/12) |
Navier-Stokes equations working sheet (posted 1/27/12) |
CHAPTER 2: CARDIOVASCULAR PHYSIOLOGY |
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| Ch2. Cardiovascular physiology (posted 1/30/12) |
CHAPTER 3: BLOOD RHEOLOGY |
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| Ch3. Blood rheology (posted 2/08/12) |
CHAPTER 4: HUMAN CIRCULATION BIOMECHANICS |
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| Ch4. Human Circulation Biomechanics (posted 2/17/12) |
CHAPTER 5: FLUID STRUCTURE INTERACTION MODELING |
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| Ch5. FSI theory (posted 2/27/12) |
CAD model for CFD (posted 3/02/12) |
CAD model for FEA (posted 3/02/12) |
Workshop syllabus (posted 3/19/12) |
FEA setup (posted 3/19/12) |
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| CFD setup (posted 3/19/12) |
FSI setup (posted 3/19/12) |
CHAPTER 6: HUMAN CIRCULATION FLUID MECHANICS |
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| Ch6. Human Circulation Fluid Mechanics - part a) (posted 2/24/12) |
Ch6. Human Circulation Fluid Mechanics - part b) (posted 3/30/12) |
Windkessel model (posted 3/30/12) |
Moens-Korteweg relationship (posted 3/30/12) |
Womersley model (posted 3/30/12) |
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| Ch6. Womersley solution (supplement) (posted 4/17//12) |
Pulsatile flow in elastic tube - part 1 (posted 4/17/12) |
Pulsatile flow in elastic tube - part 2 (posted 4/19/12) |
CHAPTER 7: FLUID DYNAMICS MEASUREMENT TECHNIQUES |
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| Ch7. Fluid dynamics measurement techniques (posted 4/23/12) |