Complex biomedical modeling efforts include predictive multiscale simulations consisting of different submodels at each scale, scalable parallelism for heterogeneous dynamical simulations, a data-rich environment with experimentally determined model parameters and, finally, distributed multidisciplinary research teams and resources. The goal of this workshop is to bring together researchers in biomedical field, bioengineering, computational and mathematical biology and biophysics to discuss recent developments in biomedical modeling as well as current and possible future collaborations. Some of the topics to be discussed are: thrombus formation, bioimaging, study of osteoporosis.

SPEAKERS:

Gary An
Department of Surgery, Northwestern University Feinberg School of Medicine
"Agent-based Instantiation of Medical Knowledge: The Road to a Biomedical Knowledge Ecology"

Danny Chen
Department of Computer Science and Engineering, University of Notre Dame
"Computer-Assisted Radiation Cancer Treatment: Computational Problems and Algorithmic Solutions"

Jake Chen
Department of Informatics and Computer Science, Indiana University School of Informatics, Founding Director of Indiana Center for Systems Biology and Personalized Medicine
"Molecular Connectivity and Network Biology Tools for Complex Disease Studies"

Scott Christley
Department of Mathematics, University of Notre Dame
"Multiscale Discrete Stochastic Agent-based Model of Limb Chondrogenesis"

Sherry Clendenon
Department of Medicine, Division of Nephrology, Indiana University School of Medicine
"4D Light Microscopy Image Acquisition, Visualization and Analysis"

Tamim Diab
Department of Anatomy and Cell Biology, Indiana University School of Medicine
"The Role of Damage Morphology in Age-Related Increase in Bone Fragility"

Scott Emrich
Department of Computer Science and Engineering, University of Notre Dame
"Lean on Me:  Comparative Anopheles Genomics"

Michael Ferdig
Department of Biological Sciences, University of Notre Dame
"Inheritance of Gene Expression Levels in Malaria Parasites Point to Regulatory Hotspots"

Michael Ferkowicz
Wells Center for Pediatric Research, Indiana University School of Medicine
"The Emergence and Early Development of the Murine Embryonic Hembryonic Hemato/vascular System"

Holly Goodson
Department of Chemistry and Biochemistry, University of Notre Dame
"Biological Insights from Computational Modeling of Microtubule Dynamics"

Jesus Izaguirre
Department of Computer Science and Engineering, University of Notre Dame
"Using Structural and Network Information to Predict Protein Domain Interactions"

Dayu Lv
Department of Aerospace and Mechanical Engineering, University of Notre Dame
"A Mathematical Model for Human Glucose Metabolism"

Greg Madey
Department of Computer Science and Engineering, University of Notre Dame
"Bioinformatic and Public Health Research Databases, Collaborative Environments, and Virtual Organizations"

Sean Mooney
Assistant Professor of Medical and Molecular Genetics, Indiana University School of Medicine
"Understanding the Biochemical Effects of Genetic Variation Data Using Computational Biology and Informatics"

Glen Niebur
Department of Aerospace and Mechanical Engineering, University of Notre Dame
"TBA"

Chris Oldfield
Center for Computational Biology and Bioinformatics, Indiana University School of Medicine
"Binding to Multiple Partners in Protein-Protein Interaction Networks"

Charles Penninger
Department of Aerospace and Mechanical Engineering, University of Notre Dame
"An Investigation in the Cellular Mechanisms of Bone Remodeling"

Pedro Romero
Indiana University School of Informatics
"Alternative Splicing Generates Alternative Biological Networks: Analyzing Tissue-Specific and Disease-Specific Variant Networks"

Elliot Rosen and Zhiliang Xu
(Rosen) Division of Molecular Genetrics and Gene Therapy, Department of Medical and Molecular Genetics, Indiana University School of Medicine (Xu) Department of Mathematics, University of Notre Dame
"Complimentary Experimental and Computational Vascular Injury Models to Study Thrombogenesis"

Leonid Rubchinsky
Department of Mathematical Science, Stark Neurosciences Research Institute, Indiana University School of Medicine
"Dynamics of Basal Ganglia Networks in Parkinson's Disease: Models and Experiments"

Zoltan Toroczkai
Department of Physics, University of Notre Dame
"Energy Landscape Networks and Protein Folding"

Dmitry Traktuev
Indiana Center for Vasular Biology and Medicine, IUPUI
"Alliance of Blood Derived Endothelial Cells and Adipose Stromal Cells in Human Vasculogenesis: Timecourse and Stability of Neovasculature"