Welcome to the Genomics Core Facility

We provide DNA fragment length analysis, high-throughput next generation and traditional Sanger sequencing, as well as Affymetrix, NimbleGen and custom-printed microarray services. Consultation with Genomics Core personnel is necessary before any microarray or 454 sequencing services will be provided. PIs submitting grants that will incorporate genomics work through the core facility are strongly encouraged to speak with John to discuss experiments and obtain a letter of support. The Genomics Core Facility is an approved Indiana CTSI core facility. Our policies for collaborative core users are available here.

Check the calendar to see when facility personnel are occupied.

We are also closely associated with the Notre Dame Bioinformatics Core Facility and can assist users interested in taking advantage of the bioinformatics and computing expertise they provide. Rory, the bioinformatics core technician, is available for assistance with custom bioinformatics and sequencing data analysis. Erliang, the bioinformatics core managing director, is available for assistance with microarray data analysis. Email them to schedule a meeting time if you would like to speak with them:
Rory - rcarmich@nd.edu
Erliang - ezeng@nd.edu
The bioinformatics core has a wiki online as a place to gather feedback and suggestions (you'll need to load their security certificate or add a security exception to use the site). Email Rory if you'd like to learn how to use this.

Recent updates

12/14/2011 - Addition information has been added to the Services page defining optimal sample concentration when submitting PCR products for full service sequencing.

10/4/2011 - Our policies for collaborative core users are now posted.

9/22/2011 - The Genomics and Bioinformatics Cores have a user survey posted. Please provide feedback through this survey to let us know how we're doing and how we can improve our services.

9/2/2011 - A new Affymetrix order form with updated information has been uploaded.

8/29/2011 - The Indiana CTSI Pilot Funding program awards up to $10,000 for services from CTSI approved cores including the Notre Dame Genomics Core Facility. The deadline is October 12, 2011 @ 5pm. More information is available at the Indiana CTSI website (Notre Dame or IU login required; you may need to add an exception for the security certificate provided by Indiana University).

7/26/2011 - Please note that some service pricing has changed. New service rates for fiscal year 2011-2012 are available here (Notre Dame login required; otherwise, please contact John or Brent about pricing)

6/29/2011 - The 454 sample requirements on the Services page have been updated to reflect 454's rapid library prep protocol.

4/7/2011 - The Genomics Core has acquired a Covaris S220 high-intensity acoustic transducer. Contact John if you are interested in using this equipment.

Older updates

- Our redo policy for full service Sanger sequencing is now posted on the Services page.

- Sequencher DNA Sequence Assembly Software is available for on-campus users through the OIT Software Download page.
To use this software, a computer must be connected to the Notre Dame network and have KeyAccess Client software installed (also available through the OIT Software Download page).

- Order forms for Affymetrix and Bioanalyzer services and updated descriptions have been added to the Services page.

- Order forms for full service DNA sequencing and ready to run sequencing/fragment analysis and a list of currently stocked universal primers have been posted to the Services page.