1.
Hesek, D.; Hembury, G. A.;
Taniguchi, S.; Inoue, Y.Photosubstitution of ligand of ruthenium complex with
retention of configuration. Jpn. Kokai Tokkyo Koho, No: 2002193936
(14pp), 2002.
2.
Ishida, H.; Hesek, D.; Inoue, Y. Spectrophotometry and its
combined cells having plural branches with different optical-path length.
Jpn. Kokai Tokkyo Koho, JP3750011, 2005 (App.No:2001147195, 7 pp, 2001).
certificate of
patent
3.
Hesek, D.; Inoue, Y.; Ishida,
H.Photochromic cationic metal complex materials based on p-p interaction and
method for isomerization thereof. Jpn. Kokai Tokkyo Koho, No:
2001139585 (10 pp), 2001.
4.
Ishida, H.; Hesek, D.; Inoue, Y.Preparation of metal bipyridine
complexes and amino acid-modified metal complexes. Jpn. Kokai Tokkyo
Koho, No: 2001039995 (9pp), 2001.
5.
Hesek, D.; Inoue, Y.; Ishida,
H.One-pot preparation of cationic metal complexes of tris(2,2'-bipyridine
derivative) and their chiral complexes. Jpn. Kokai Tokkyo Koho, JP3750010, 2005 (App.No:
2001039994, 17 pp, 2001).
certificate of patent
6.
Ishida, H.; Hesek, D.; Inoue, Y.; Everitt, S. R. L.Preparation
of metal complex cations useful for asymmetric synthesis of metal complexes.
Jpn. Kokai Tokkyo Koho, No: 2000264895, (19 pp),
2000.
7.
Szemes, F.; Hesek, D.; Rybar, A.; Tegza, M.; Simkova, M.;
Bachraty, F. Method of preparing 1-(2,6-dimethylphenoxy)2-propylamine
(mexiletine). Czech CS 275,513 C.A. 119: P 203.135w
(1993).
8.
Gomory, J.; Hesek, D.; Tegza, M.; Smahovsky, V.; Kacina, R.;
Kmetty, G. Method of production of 7-(2-hydroxyethyl)theophylline[etofylline]
by alkylation of theophylline with haloethanols and bases. Czech CS
267,313 (15 July 1991). C.A. 116: P 59 097d (1992).
9.
Rybar, A.; Tegza, M.; Repas, M. C.; Szemes, F.; Frimm, R.; Hesek,
D.; Guttmann, M.; Turcani, P.; Mahrla, Z. Two-step alkylation method for
the preparation of
3-methyl-1-(5-oxohexyl)-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione
[propentofylline]. Czech CS 270,545 (25 Jun 1991). C.A. 117: P
90 053f (1992).
10. Rybar, A.; Tegza, M.;
Repas, M. C.; Szemes, F.; Frimm, R.; Hesek, D.; Guttmann, M. One-pot
synthesis of 3-methyl-7-prophyl-3,7-dihydro-1H-purine-2,6-dione in protic
solvents. Czech CS 271,988 (24 Sep 1991). C.A. 117: P 171 090t
(1992).
11. Rybar, A;. Repas, M.;
Tegza, M.; Hesek, D.; Nevydal, J.; Frimm, R.; Szemes, F. Preparation of
the vasodilator intermediate
7-(n-propyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione via alkylation with
propyl halides. Czech CS 263,595 (15 July 1988). C.A. 113: P
40721 (1990).
12. Rybar, A.; Repas, M.;
Tegza, M.; Hesek, D.; Frimm, R.; Szemes, F.; Greiplova, E. Preparation
of 6-amino-5-bromo-1-methyl-1H-pyrimidine-2,4-dione as vasodilator
propentofylline intermediate. Czech CS 267.786 (30 July
1989). C.A. 114: P 228941 (1990).
13. Rybar, A.; Repas, M.;
Tegza, M.; Szemes, F.; Frimm, R.; Hesek, D.; Greiplova, E. Method for
the preparation of 6-amino-5-bromo-1-methyl-1H-pyrimidine-2,4-dione as an
intermediate for the vasodilator propentofylline. Czech CS 267.380 (14
Dec 1990). C.A. 114: P 231 997 (1990).
14. Rybar, A.; Tegza, M.;
Repas, M.; Hesek, D.; Frimm, R.; Szemes, F.; Guttmann, M. Method of
preparing 3-methyl-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione. Czech CS
267.796 (02 July 1990). C.A. 114: P 185 144 (1990).
15. Rybar, A.; Repas, M.;
Hesek, D.; Frimm, R;. Tegza, M.; Szemes, F. A method for the
preparation of 3-methyl-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione as an
intermediate for vasodilator propentofylline. Czech CS 267,379 (14 Dec
1990). C.A. 115: P 207 763 (1990).
16. Rybar, A.; Repas, M.;
Tegza, M.; Szemes, F.; Frimm, R.; Hesek, D.; Guttmann, M. N-methylation
of 3-methyl-3,7-dihydro-1H-purine-2,6-dione by methyl chloride. Czech
CS 267,100 (14 Dec 1990). C.A. 115: P 279 704 (1990).
17. Rybar, A.; Repas, M.;
Tegza, M.; Hesek, D.; Frimm, R.; Szemes, F.; Turcani, P.; Mahrla, Z. A
method for the preparation of
3-methyl-1-(5-oxohexyl)-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione as an
intermediate for vasodilator propentofylline. Czech CS 266,291 (13 July
1990). C.A. 115: P 207 764 (1990).
18. Rybar, A;. Repas, M.;
Tegza, M.; Hesek, D.; Nevydal, J.; Frimm, R.; Szemes, F. Preparation of
the vasodilator intermediate
7-(n-propyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione via alkylation of
purinedione salts with propyl halides. Czech CS 263,200 (15 July
1988). C.A. 113: P 40720 (1990).
19. Hesek, D.; Tegza, M.; Rybar, A.;
Szemes, F.; Jezek, L.; Simko, M. Preparation of
1-(2,6-dimethylphenoxy)-2-propanone as an anthiarrithmic drug intermediate.
Czech CS 246,872 (15. Jan 1988). C.A. 111: P 96 827j
(1989).
20. Rybar, A.; Repas, M.;
Szemes, F.; Nevydal, J.; Hesek, D. Process for preparation of
5,6-diamino-1-methyl-2,4(1H,3H)-pyrimidinedione as a pharmaceutical
intermediate. Czech CS 261.447 (30 July 1989). C.A. 112: P 261.447
(1990).
21. Hesek, D.; Szemes, F.; Tegza,
M.; Rybar, A.; Losova, O.; Martvon, A.; Simkova, M. Purification of the
anthiarrithmic 1-(2,6-dimethylphenoxy)-2-aminopropane hydrochloride
[mexiletine HCl]. Czech CS 250,577 (15 July 1988). C.A. 110: P
94 677r (1989).
22. Nevydal, J.; Manduch
M.; Siska, K.; Frimm, R.; Gattnar, O.; Hesek, D.; Rybar, A. Preparation
of 1-(2,6-dimethylphenoxy)-2-propanone as an intermediate for pharmaceutics.
Czech CS 245,189 (15. Oct 1987). C.A. 109: P 128 579g
(1988).
23. Szemes, F.; Rybar, A.;
Hesek, D.; Tegza, M.; Kosalk,o R. Preparation of
1-(2,6-dimethylphenoxy)-2-propylamine as an anthiarrithmic drug. Czech
CS 239,418 (16 Apr 1987). C.A. 109: P 92 467c (1988).
24. Szemes, F.; Tegza, M.;
Hesek, D.; Rybar, A.; Zlatinsky, E. Preparation of
1-(2,6-dimethylphenoxy)-2-propanol as intermediate for pharmaceuticals.
Czech CS 235,184 (15. Feb 1987). C.A. 108: P 5 683h
(1988).
25. Tegza, M.; Hesek,
D.; Rybar, A.; Kosalko, R.; Martvon A. Preparation of
1-(2,6-dimethylphenoxy)-2-propylamine. Czech CS 230,305 (15. Oct
1986). C.A. 108: P 131 2873n (1986).
26. Janda, L.; Voticky,
Z.; Ryba,r A.; Hesek, D. Ethyl
5-(5-phenyl-2-furyl)tetrazole-1-acetates. Czech CS 232,343 (15 July
1986). C.A. 106: P 33 069q (1987).
27. Hesek, D.; Tegza, M.; Rybar, A.;
Szemes, F.; Kosalko, R.; Martvon, A. 1-(2,6-Dimethylphenoxy)-2-propanone.
Czech. CS 223,436 (15 Mar 1986). C.A. 105: P 226 047u
(1986).
28. Hesek, D.; Tegza, M.; Ryba,r A.;
Martvon, A.; Kosalko, R. 1-(2,6-Dimethyphenoxy)-2-propylazide. Czech.
CS 216,896 (31 Okt 1984). C.A. 102: P 220 562z (1984).

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