The List of Published Papers

The Latest Work Papers Patents References

1979-2011

123.    Jeong Soon Park, Woo Cheol Lee, Kwon Joo Yeo, Kyoung-Seok Ryu, Malika Kumarasiri, Dusan Hesek, Mijoon Lee, Shahriar Mobashery, Jung Hyun Song, Seung Il Kim, Je Chu Lee, Chaejoon Cheong, Young Ho Jeon, and Hye-Yeon Kim. Mechanism of Anchoring of OmpA protein to the Cell Wall Peptidoglycan of the Gram-Negative Bacterial Outer Membrane.  FASEB J. 2011, (In Press).

122.     Cesar Carrasco-López, Alzoray Rojas-Altuve, Weilie Zhang, Dusan Hesek, Mijoon Lee, Sophie Barbe, Isabelle André, Pilar Ferrer, Noella Silva-Martin, German R. Castro, Martín Martínez-Ripoll, Shahriar Mobashery, and Juan A. Hermoso. Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism. J. Biol. Chem. 2011, 286, 31714-31722.

121.     Oleg Borbulevych, Malika Kumarasiri, Brian Wilson, Leticia I. Llarrull, Mijoon Lee, Dusan Hesek, Qicun Shi, Jeffrey Peng, Brian M. Baker, and Shahriar Mobashery. Lysine N-Decarboxylation Switch and Activation of the B-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus. J. Biol. Chem. 2011, 286, 31466-31472.

120.     S. Mobashery, D. Hesek, and M. Chang. Phthalanilate compounds and methods of use. (University of Notre Dame du Lac, USA). 2011:266847, 2011, 146 pp. (English).

119.     B. Maestro, L. Novakova, D. Hesek, M. Lee, E. Leyva, S. Mobashery, J. M. Sanz, and P. Branny. Recognition of peptidoglycan and beta-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae. FEBS Lett., 2011, 585, 357-363.

118.     M. Lee, D. Hesek, I. M. Shah, A. G. Oliver, J. Dworkin and S. Mobashery. Synthetic Peptidoglycan Motifs for Germination of Bacterial Spores. ChemBioChem, 2010, 11, 2525-2529.

117.     T. Yamaguchi, D. Hesek, M. Lee, A. G. Oliver, and S. Mobashery. Sulfonylation-Induced N- to O-Acetyl Migration in 2-Acetamidoethanol Derivatives. J. Org. Chem., 2010, 75, 3515-3517.

116.     S. A. Testero, P. I. O'Daniel, Q. C. Shi, M. Lee, D. Hesek, A. Ishiwata, B. C. Noll, and S. Mobashery. Regiospecific Syntheses of 6 alpha-(1R-Hydroxyoctyl)penicillanic Acid and 6 beta-(1R-Hydroxyoctyl) penicillanic Acid as Mechanistic Probes of Class D beta-Lactamases. Org. Lett., 2009, 11, 2515-2518.

115.     M. J. Lee, W. L. Zhang, D. Hesek, B. C. Noll, B. Boggess and S. Mobashery. Bacterial AmpD at the Crossroads of Peptidoglycan Recycling and Manifestation of Antibiotic Resistance. J. Am. Chem. Soc., 2009, 131, 8742-8743.

114.     M. Lee, D. Hesek, B. C. Noll and S. Mobashery. Key side products due to reactivity of dimethylmaleoyl moiety as amine protective group. Chem. Pap., 2009, 63, 592-597.

113.     M. Lee, G. Celenza, B. Boggess, J. Blase, Q. Shi, M. Toth, M. M. Bernardo, W. R. Wolter, M. A. Suckow, D. Hesek, B. C. Noll, R. Fridman, S. Mobashery and M. Chang. A Potent Gelatinase Inhibitor with Anti-Tumor-Invasive Activity and its Metabolic Disposition. Chem. Biol. Drug Des., 2009, 73, 189-202.

112.     D. Hesek, M. Lee, W. L. Zhang, B. C. Noll and S. Mobashery. Total Synthesis of N-Acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and Evaluation of Its Turnover by AmpD from Citrobacter freundi. J. Am. Chem. Soc., 2009, 131, 5187-5193.

111.     D. Hesek, M. Lee, B. C. Noll, J. F. Fisher and S. Mobashery. Complications from Dual Roles of Sodium Hydride as a Base and as a Reducing Agent. J. Org. Chem., 2009, 74, 2567-2570.

110.     M. Gooyit, M. Lee, D. Hesek, B. Boggess, A. G. Oliver, R. Fridman, S. Mobashery and M. Chang. Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenylsulfonyl)ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors. Chem. Biol. Drug Des., 2009, 74, 535-546.

109.     C. Forbes, Q. C. Shi, J. F. Fisher, M. Lee, D. Hesek, L. I. Llarrull, M. Toth, M. Gossing, R. Fridman and S. Mobashery. Active Site Ring-Opening of a Thiirane Moiety and Picomolar Inhibition of Gelatinases. Chem. Biol. Drug Des., 2009, 74, 527-534.

108.     Y. Chen, W. L. Zhang, Q. C. Shi, D. Hesek, M. Lee, S. Mobashery and B. K. Shoichet. Crystal Structures of Penicillin-Binding Protein 6 from Escherichia coli. J. Am. Chem. Soc., 2009, 131, 14345-14354.

107.     A. Villegas-Estrada, M. Lee, D. Hesek, S. B. Vakulenko and S. Mobashery. Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: Potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics. J. Am. Chem. Soc., 2008, 130, 9212-9213.

106.     M. Lee, D. Hesek, Q. Shi, B. C. Noll, J. F. Fisher, M. Chang and S. Mobashery. Conformational analyses of thiirane-based gelatinase inhibitors. Bioorg. Med. Chem. Lett., 2008, 18, 3064-3067.

105.     M. Lee, D. Hesek   and S. Mobashery. Synthetic efforts in preparation of components of the bacterial cell wall. ACS Symp. Ser., 2008, 990, 54-78.

104.     D. Hesek, M. Lee, T. Yamaguchi, B. C. Noll and S. Mobashery. Facile preparation of a highly functionalized tetrahydropyran by catalytic hydrogenation of an oxazoline. J. Org. Chem., 2008, 73, 7349-7352.

103.     M. Suvorov, M. Lee, D. Hesek, B. Boggess and S. Mobashery. Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall. J. Am. Chem. Soc., 2008, 130, 11878-11879.

102.     I. Perez-Dorado, N. E. Campillo, B. Monterroso, D. Hesek, M. Lee, J. A. Paez, P. Garcia, M. Martinez-Ripoll, J. L. Garcia, S. Mobashery, M. Menendez and J. A. Hermoso. Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1. J. Biol. Chem., 2007, 282, 24990-24999.

101.     D. Kling, D. Hesek, Q. C. Shi and S. Mobashery. Design and synthesis of a structurally constrained aminoglycoside. J. Org. Chem., 2007, 72, 5450-5453.

100.     C. Kim, A. Villegas-Estrada, D. Hesek   and S. Mobashery. Mechanistic characterization of the bifunctional aminoglycoside-modifying enzyme AAC(3)-Ib/AAC(6 ')-Ib ' from Pseudomonas aeruginosa. Biochemistry, 2007, 46, 5270-5282.

99.       C. Fuda, M. Suvorov, Q. C. Shi, D. Hesek, M. Lee and S. Mobashery. Shared functional attributes between the mecA gene product of Staphylococcus sciuri and penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus. Biochemistry, 2007, 46, 8050-8057.

98.       S. Cho, Q. Wang, C. P. Swaminathan, D. Hesek, M. Lee, G. J. Boons, S. Mobashery and R. A. Mariuzza. Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. USA, 2007, 104, 8761-8766.

97.       M. Rekharsky, D. Hesek, M. Lee, S. O. Meroueh, Y. Inoue and S. Mobashery. Thermodynamics of interactions of vancomycin and synthetic surrogates of bacterial cell wall. J. Am. Chem. Soc., 2006, 128, 7736-7737.

96..      S. O. Meroueh, K. Z. Bencze, D. Hesek, M. Lee, J. F. Fisher, T. L. Stemmler and S. Mobashery. Three-dimensional structure of the bacterial cell wall peptidoglycan. Proc. Natl. Acad. Sci. USA, 2006, 103, 4404-4409.

95.       C. Kim, D. Hesek, J. Zajicek, S. B. Vakulenko and S. Mobashery. Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3 '')-Ii/AAC(6 ')-IId from Serratia marcescens. Biochemistry, 2006, 45, 8368-8377.

94.       D. Hesek, M. Toth, S. O. Meroueh, S. Brown, H. Zhao, W. Sakr, R. Fridman and S. Mobashery. Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples. Chem Biol, 2006, 13, 379-386.

93.       D. Hesek, M. Toth, V. Krchnak, R. Fridman and S. Mobashery. Synthesis of an inhibitor-tethered resin for detection of active matrix metalloproteinases involved in disease. J. Org. Chem., 2006, 71, 5848-5854.

92.       D. Hesek, B. C. Noll and S. Mobashery. Side reaction of significance in preparation of peptide- or peptidomimetic-based hydroxamate enzyme inhibitors. J. Org. Chem., 2006, 71, 2885-2887.

91.       C. Fuda, D. Hesek, M. Lee, W. Heilmayer, R. Novak, S. B. Vakulenko and S. Mobashery. Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus. J. Biol. Chem., 2006, 281, 10035-10041.

90.       C. Fuda, D. Hesek, M. Lee, K. Morio, T. Nowak and S. Mobashery. Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall. J. Am. Chem. Soc., 2005, 127, 2056-2057.

89.       M. Toth, P. Osenkowski, D. Hesek, S. Mobashery and R. Fridman. Purification and detection strategies of MT1-MMP from tumor tissue samples. Int Union Biochem Molecular Biol,  IUBMB 50th Anniversary Symposium Budapest, HUNGARY, JUL 02-07, 2005. FEBS J., 2005, 272, 148-148.

88.       M. Toth, P. Osenkowski, D. Hesek, S. Brown, S. Meroueh, W. Sakr, S. Mobashery and R. Fridman. Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase. Biochem. J, 2005, 387, 497-506.

87.       M. Lee, D. Hesek   and S. Mobashery. A practical synthesis of nitrocefin. J. Org. Chem., 2005, 70, 367-369.

86.       D. Hesek, M. Suvorov, K. Morio, M. Lee, S. Brown, S. B. Vakulenko and S. Mobashery. Synthetic peptidoglycan substrates for penicillin-binding protein 5 of gram-negative bacteria. J. Org. Chem., 2004, 69, 778-784.

85.       D. Hesek, M. J. Lee, K. I. Morio and S. Mobashery. Synthesis of a fragment of bacterial cell wall. J. Org. Chem., 2004, 69, 2137-2146.

84..      W. R. Browne, D. Hesek, J. F. Gallagher, C. M. O'Connor, J. S. Killeen, F. Aoki, H. Ishida, Y. Inoue, C. Villani and J. G. Vos. Structural and photophysical characterisation of coordination and optical isomers of mononuclear ruthenium(II) polypyridyl 1,2,4-triazole complexes. Dalton Trans., 2003 2597-2602.

83.       M. Lee, D. Hesek, M. Suvorov, W. Lee, S. Vakulenko and S. Mobashery. A mechanism-based inhibitor targeting the DD-transpeptidase activity of bacterial penicillin-binding proteins. J. Am. Chem. Soc., 2003, 125, 16322-16326.

82.       M. Oelgemoller, K. Fukui, D. Hesek, F. Aoki, M. Niki and Y. Inoue. The formation of spiro-bridged dimers of cyclooctane-1,2-dicarbonyl compounds via domino aldol-cycloalkylation. Heterocycles, 2002, 57, 741-742.

81.       D. Hesek, G. Henbrey, S. Taniguchi and Y. Inoue. Photosubstitution of ligand of ruthenium complex with retention of configuration. (Foundation for Scientific Technology Promotion, Japan). 2002:515663, 2002, 14 pp. (Japanese).

80.       D. Hesek, G. A. Hembury, M. G. B. Drew and Y. Inoue. Controlled specific ligand substitution and chiroptical properties of ruthenium bis(bipyridine) nitrosoarene complexes. Bull. Chem. Soc. Jpn., 2002, 75, 335-338.

79.       M. Oelgemoller, A. G. Griesbeck, J. Lex, A. Haeuseler, M. Schmittel, M. Niki, D. Hesek   and Y. Inoue. Structural, CV and IR spectroscopic evidences for preorientation in PET-active phthalimido carboxylic acids. Org. Lett., 2001, 3, 1593-1596.

78.       H. Ishida, D. Hesek, T. Nanmyo, F. Aoki and Y. Inoue. Design and synthesis of amino acid- or peptide-modified ruthenium tris(bipyridine) complexes for photoresponsive molecular devices. Pept. 2000, Proc. Eur. Pept. Symp., 26th, 2001 139-140.

77.       H. Ishida, D. Hesek   and Y. Inoue. Preparation of metal bipyridine complexes and amino acid-modified metal complexes. (Foundation for Scientific Technology Promotion, Japan; Japan Science and Technology Agency). 2001:106384, 2001, 9 pp. (Japanese).

76.       H. Ishida, D. Hesek   and Y. Inoue. Spectrophotometry and its combined cells having plural branches with different optical-path length. (Foundation for Scientific Technology Promotion, Japan). 2001:390328, 2001, 7 pp. (Japanese) JP3750011.

75.       D. Hesek, Y. Inoue and H. Ishida. One-pot preparation of cationic metal complexes of tris(2,2'-bipyridine derivative) and their chiral complexes. (Foundation for Scientific Technology Promotion, Japan; Japan Science and Technology Agency). 2001:107896, 2001, 17 pp. (Japanese) JP3750010.

74.       D. Hesek, Y. Inoue and H. Ishida. Photochromic cationic metal complex materials based on pi-pi interaction and method for isomerization thereof. (Foundation for Scientific Technology Promotion, Japan; Japan Science and Technology Agency). 2001:372162, 2001, 10 pp. (Japanese).

73.       H. Ishida, D. Hesek, F. Aoki and Y. Inoue. Molecular design, synthesis and photochemical function of amino acid- or peptide-modified ruthenium tris(bipyridine) complexes. Peptide Science, 2001, 37th, 353-354.

72.       D. Hesek, G. A. Hembury, M. G. Drew, S. Taniguchi and Y. Inoue. Ligand selective monosubstitution with complete enantiomeric retention in ruthenium bis(bipyridine) complexes. Inorg. Chem., 2001, 40, 2478-2479.

71.       K. Fukui, D. Hesek, M. Oelgemoller and Y. Inoue. Crystal structure of N-cyclooctylidene-N '-(2,4-dinitrophenyl)-hydrazine, C14H18N4O4. Z. Krist-New Cryst St, 2001, 216, 661-662.

70.       D. Hesek, G. A. Hembury, M. G. B. Drew, V. V. Borovkov and Y. Inoue. Photochromic atropisomer generation and conformation determination in a ruthenium bis(bipyridine) phosphonite gamma-cyclodextrin system. J. Am. Chem. Soc., 2001, 123, 12232-12237.

69.       H. Ishida, D. Hesek, S. Everitt and Y. Inoue. Preparation of metal complex cations useful for asymmetric synthesis of metal complexes. (Foundation for Scientific Technology Promotion, Japan). 2000:677406, 2000, 18 pp. (Japanese).

68.       D. Hesek, Y. Inoue, H. Ishida, S. R. L. Everitt and M. G. B. Drew. The first asymmetric synthesis of chiral ruthenium tris(bipyridine) from racemic ruthenium bis(bipyridine) complexes. Tetrahedron Lett., 2000, 41, 2617-2620.

67.       D. Hesek, Y. Inoue, S. R. L. Everitt, H. Ishida, M. Kunieda and M. G. B. Drew. Diastereoselective preparation and characterization of ruthenium bis(bipyridine) sulfoxide complexes. Inorg. Chem., 2000, 39, 317-324.

66.       D. Hesek, Y. Inoue, M. G. Drew, P. D. Beer, G. A. Hembury, H. Ishida and F. Aoki. Acid-promoted rearrangement of carbonate functionality anchored to the lower rim of a Calix. Org Lett, 2000, 2, 2237-2240.

65.       D. Hesek, G. A. Hembury, M. G. B. Drew, S. Taniguchi and Y. Inoue. Atropisomer and diastereomer generation and control in rutheninm bis(bipyridine) phosphonite complexes. J. Am. Chem. Soc., 2000, 122, 10236-10237.

64.       F. Aoki, D. Hesek, H. Ishida and Y. Inoue. Chromatographic chiral separation of ruthenium tris(bipyridine) complexes. Chromatography, 2000, 21(2), 133-134.

63.       F. Aoki, D. Hesek, H. Ishida and Y. Inoue. Optical resolution of ruthenium tris(bipyridine) complexes by normal- and reversed-phase HPLC. Chromatography, 2000, 21(4), 366-367.

62.       D. Hesek, Y. Inoue, S. R. L. Everitt, H. Ishida, M. Kunieda and M. G. B. Drew. Novel synthetic routes to several new, differentially substituted ruthenium tris(4,4 '-disubstituted-2,2-bipyridine) complexes. Inorg. Chem., 2000, 39, 308-316.

61.       D. Hesek, Y. Inoue, S. R. L. Everitt, H. Ishida, M. Kunieda and M. G. B. Drew. Conversion of a new chiral reagent Delta-[Ru(bpy)(2)(dmso)Cl] PF6 to Delta-[Ru(bpy)(2)(dmbpy)]PF6Cl with 96.8% retention of chirality (dmbpy = 4,4 '-dimethyl-2,2 '-bipyridine). Chem. Commun., 1999, 403-404.

60.       H. Ishida, T. Nanmyo, D. Hesek, F. Aoki and Y. Inoue. Molecular design of metal complexes bearing three different peptide modified ligands: towards protein function appearance. Peptide Science, 1999, 36th, 71-74.

59.       C. J. Kepert, M. J. Rosseinsky, D. Hesek   and P. D. Beer. Robust microporous molecular frameworks which retain structural integrity upon template loss. Mater Res Soc Symp P, 1999, 547, 512-519.

58.       P. D. Beer, D. Hesek, K. C. Nam and M. G. B. Drew. Anion recognition properties of new upper-rim cobaltocenium calix[4]arene receptors. Organometallics, 1999, 18, 3933-3943.

57.       D. Hesek, Y. Inoue and S. R. L. Everitt. Conformational switching in the thermal and photochemical synthesis of cis- and trans-ruthenium bis(bipyridine) sulfoxide complexes. Chem. Lett., 1999 109-110.

56.       D. Hesek, Y. Inoue, S. R. L. Everitt, H. Ishida, M. Kunieda and M. G. B. Drew. Preparation and structural elucidation of novel cis ruthenium(II) bis(bipyridine) sulfoxide complexes. J. Chem. Soc., Dalton Trans., 1999 3701-3709.

55.       P. D. Beer, M. G. B. Drew, D. Hesek, M. Kan, G. Nicholson, P. Schmitt, P. D. Sheen and G. Williams. A neutral uranyl dimeric complex and remarkable extraction properties of a 1-acid 3-diethyl amide substituted calix[4]arene ligand. J. Chem. Soc., Dalton Trans., 1998 2783-2785.

54.       D. Hesek, Y. Inoue, S. R. L. Everitt, M. Kunieda, H. Ishida and M. G. B. Drew. High yield preparation of a novel tetrakis[ruthenium tris(bipyridine)]calix[6]arene derivative with good diastereomeric purity. Tetrahedron: Asymmetry, 1998, 9, 4089-4097.

53.       C. J. Kepert, D. Hesek, P. D. Beer and M. J. Rosseinsky. Desolvation of a novel microporous hydrogen-bonded framework: Characterization by in situ single-crystal and powder X-ray diffraction. Angew. Chem., Int. Ed., 1998, 37, 3158-3160.

52.       M. J. Kan, G. Nicholson, I. Horn, G. Williams, P. D. Beer, P. Schmitt, D. Hesek, M. G. B. Drew and P. Sheen. Neutral uranium dimer complexes and selective extraction properties of a new para-tertiary butyl 1,3-acid-diethyl amide substituted calix[4]arene ligand. Nucl Energ-J Br Nucl, 1998, 37, 325-329.

51.       P. D. Beer, M. G. B. Drew, D. Hesek   and K. C. Nam. A new carboxylate anion selective cobaltocenium calix[4]arene receptor. Chem. Commun., 1997 107-108.

50.       F. Szemes, D. Hesek, Z. Chen, S. W. Dent, M. G. B. Drew, A. J. Goulden, A. R. Graydon, A. Grieve, R. J. Mortimer, T. Wear, J. S. Weightman and P. D. Beer. Synthesis and characterization of novel acyclic, macrocyclic, and calix[4]arene ruthenium(II) bipyridyl receptor molecules that recognize and sense anions. Inorg. Chem., 1996, 35, 5868-5879.

49.       D. Hesek, A. Rybar, J. Alfoldi, J. Bella and V. Patoprsty. Synthesis of new [1,3]diazaheterocyclo[2',1':2,3][1,3,5]thiadiazino[4,5-f]purine ring systems. Collect. Czech. Chem. Commun., 1996, 61, 1642-1646.

48.       P. D. Beer, M. G. B. Drew, D. Hesek, M. Shade and F. Szemes. Anion recognition properties of new upper-rim bis[rhenium(I) bipyridyl, ruthenium(II) bis(bipyridyl), cobaltocenium]calix[4]arene receptors dictated by lower-rim substituents. Chem. Commun., 1996, 2161-2162.

47.       P. D. Beer, M. G. B. Drew, D. Hesek   and S. M. Lacy. Acid catalysed condensation reactions of 1,3-dihydroxybenzene with new redox-active metallocene aldehydes. J. Organomet. Chem., 1996, 511, 207-215.

46.       P. D. Beer, D. Hesek, J. E. Kingston, D. K. Smith, S. E. Stokes and M. G. B. Drew. Anion Recognition by Redox-Responsive Ditopic Bis-Cobaltocenium Receptor Molecules Including a Novel Calix[4]Arene Derivative That Binds a Dicarboxylate Dianion. Organometallics, 1995, 14, 3288-3295.

45.       P. D. Beer, M. G. B. Drew, D. Hesek   and R. Jagessar. Spectral and Electrochemical Anion Sensing by a Novel 5,10,15,20-Tetrakis(R-Substituted) Porphyrin Receptor (R=C6h4nhc(O)C5h4coc5h5+Pf6-). J. Chem. Soc., Chem. Commun., 1995, 1187-1189.

44.       P. D. Beer, J. P. Danks and D. Hesek  . Synthesis, Coordination and Redox Properties of a Novel Tetrathiafulvalene Tetra(Benzo-15-Crown-5)Ether Ligand. Polyhedron, 1995, 14, 1327-1332.

43.       P. D. Beer, P. A. Gale and D. Hesek  . A Neutral Upper to Lower Rim Linked Bis-Calix[4]Arene Receptor That Recognizes Anionic Guest Species. Tetrahedron Lett., 1995, 36, 767-770.

42.       D. Hesek   and A. Rybar. [F]-Fused Purine-2,6-Diones - Synthesis of New [1,3,5]-Thiadiazepino-[3,2-F]-Purine and [1,3,6]-Thiadiazepino-[3,2-F]-Purine Ring-Systems. Monatsh. Chem., 1994, 125, 1273-1278.

41.       P. D. Beer, Z. Chen, A. J. Goulden, A. Grieve, D. Hesek, F. Szemes and T. Wear. Anion Recognition by Novel Ruthenium(Ii) Bipyridyl Calix[4]Arene Receptor Molecules. J. Chem. Soc., Chem. Commun., 1994, 1269-1271.

40.       D. Hesek   and A. Rybar. 7,8-Disubstituted [1,3]-Thiazino-[2,3-F]-Purine Derivatives. Monatsh. Chem., 1993, 124, 1143-1148.

39.       P. D. Beer, C. Hazlewood, D. Hesek, J. Hodacova and S. E. Stokes. Anion Recognition by Acyclic Redox-Responsive Amide-Linked Cobaltocenium Receptors. J. Chem. Soc., Dalton Trans., 1993, 1327-1332.

38.       P. D. Beer, M. G. B. Drew, C. Hazlewood, D. Hesek, J. Hodacova and S. E. Stokes. Dicarboxylate Anion Recognition by a Redox-Responsive Ditopic Bis(Cobalticinium) Calix[4]Arene Receptor Molecule. J. Chem. Soc., Chem. Commun., 1993, 229-231.

37.       P. D. Beer, J. P. Danks, D. Hesek   and J. F. Mcaleer. A Potassium-Selective Sulfide-Linked Redox-Active Ferrocene Ionophore That Exhibits Extraordinary Electrochemical Recognition Behavior. J. Chem. Soc., Chem. Commun., 1993, 1735-1737.

36.       F. Szemes, D. Hesek, A. Rybar, M. Tegza, M. Simko, M. Simkova, and  F. Bachraty. Method of preparing 1-(2,6-dimethylphenoxy)-2-propylamine [mexiletine]. (Vyskumny Ustav Lieciv, Czech.). 1993:603135, 1992, 6 pp. (Slovak), CS8808642A2.

35.       P. D. Beer, D. Hesek, J. Hodacova and S. E. Stokes. Acyclic Redox Responsive Anion Receptors Containing Amide Linked Cobalticinium Moieties. J. Chem. Soc., Chem. Commun., 1992, 270-272.

34.       A. Rybar, M. Tegza, M. C. Repas, F. Szemes, R. Frimm, D. Hesek   and M. Guttmann. One-pot synthesis of 3-methyl-7-propyl-3,7-dihydro-1H-purine-2,6-dione in protic solvents. (Czech.). 1992:571090, 1991, 5 pp. (Slovak).

33.       A. Rybar, M. Tegza, M. Repas, F. Szemes, R. Frimm, D. Hesek, M. Guttmann, P. Turcani, Z. Mahrla and A. Et. Two-step alkylation method for the preparation of 3-methyl-1-(5-oxohexyl)-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione (propentofylline). (Czech.). 1992:490053, 1991, 5 pp. (Slovak).

32.       D. Hesek, A. Rybar and J. Bella. New [F]-Fused Theophyllines Via Intramolecular Nucleophilic-Addition of Alkyl (E)-4-[(8-Substituted)Theophyllin-7-Yl]-2-Butenoate. Synthesis, 1991 625-628.

31.       J. Gomory, D. Hesek, M. Tegza, V. Smahovsky, R. Kacina and G. Kmetty. Method of production of 7-(2-hydroxyethyl)theophylline [etofylline] by alkylation of theophylline with haloethanols and bases. (Czech.). 1992:59097, 1991, 3 pp. (Czech).

30.       A. Rybar, M. Repas, M. Tegza, D. Hesek, R. Frimm, F. Szemes, P. Turcani and Z. Mahrla. A method for the preparation of 3-methyl-1-(5-oxohexyl)-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione as an intermediate for vasodilator propentofylline. (Czech.). 1991:607764, 1990, 6 pp. (Slovak).

29.       A. Rybar, M. Repas, M. Tegza, D. Hesek, R. Frimm, F. Szemes and E. Greiplova. Preparation of 6-amino-5-bromo-1-methyl-1H-pyrimidine-2,4-dione as vasodilator propentofylline intermediate. (Czech.). 1991:228941, 1990, 4 pp. (Slovak).

28.       A. Rybar, M. Repas, D. Hesek, R. Frimm, M. Tegza and F. Szemes. A method for the preparation of 3-methyl-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione as an intermediate for vasodilator propentofylline. (Czech.). 1991:607763, 1990, 3 pp. (Slovak).

27.       A. Rybar, D. Hesek, F. Szemes, J. Alfoldi and M. Tegza. 3,7-Dialkyl-8-Alkyl or Aryl-3,7-Dihydropurine-2,6-Diones. Collect. Czech. Chem. Commun., 1990, 55, 2257-2269.

26.       A. Rybar, M. Repas, M. Tegza, F. Szemes, R. Frimm, D. Hesek   and M. Guttmann. N-methylation of 3-methyl-3,7-dihydro-1H-purine-2,6-dione by methyl chloride. (Czech.). 1991:679704, 1990, 5 pp. (Slovak).

25.       A. Rybar, M. Tegza, M. Repas, D. Hesek, R. Frimm, F. Szemes and M. Guttmann. Method of preparing 3-methyl-7-n-propyl-3,7-dihydro-1H-purine-2,6-dione. (Czech.). 1991:185144, 1990, 4 pp. (Slovak).

24.       A. Rybar, M. Repas, M. Tegza, F. Szemes, R. Frimm, D. Hesek   and E. Greiplova. Method for the preparation of 6-amino-5-bromo-1-methyl-1H-pyrimidine-2,4-dione as an intermediate for the vasodilator propentofylline. (Czech.). 1991:631997, 1990, 3 pp. (Slovak).

22.       D. Hesek, M. Tegza, A. Rybar and F. Povazanec. New [F]-Fused Theophyllines - a Simple One-Step Synthesis of the Pyrimido[2,1-F]Purine System Via 8-Azidopurines. Synthesis, 1989 681-683.

21.       A. Rybar, M. Repas, M. Tegza, D. Hesek, J. Nevydal, R. Frimm and F. Szemes. Preparation of the vasodilator intermediate 7-(n-propyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione via alkylation of purinedione salts with propyl halides. (Czech.). 1990:440720, 1989, 5 pp. (Slovak), CS263200B1.

20.       A. Rybar, M. Repas, M. Tegza, D. Hesek, J. Nevydal, R. Frimm and F. Szemes. Preparation of the vasodilator intermediate 7-(n-propyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione via alkylation with propyl halides. (Czech.). 1990:440721, 1989, 4 pp. (Slovak), CS263595B1.

19.       A. Rybar, M. Repas, F. Szemes, J. Nevydal and D. Hesek  . Process for preparation of 5,6-diamino-1-methyl-2,4(1H,3H)-pyrimidinedione as a pharmaceutical intermediate. (Czech.). 1990:77219, 1989, 4 pp. (Slovak), CS261447B1.

18.       F. Povazanec, J. Kovac and D. Hesek  . Reactions of 5-Azido-2-Furaldehyde with 2-Substituted Anilines. Chem. Papers 1988, 42(5), 667-682

17.       F. Povazanec, D. Hesek, A. Rybar and J. Kovac. Azides and their precursors in synthesis of polycondensed heterocyclic compounds. Studies in Organic Chemistry (Amsterdam), 1988, 35, 491-492.

16.       D. Hesek, M. Tegza, A. Rybar, F. Szemes, L. Jezek and M. Simko. Preparation of 1-(2,6-dimethylphenoxy)-2-propanone as an antiarrhythmic drug intermediate. (Czech.). 1989:496827, 1988, 4 pp. (Slovak), CS246872B1.

15.       D. Hesek, F. Szemes, M. Tegza, A. Rybar, O. Losova, A. Martvon and M. Simkova. Purification of the antiarrhythmic 1-(2,6-dimethylphenoxy)-2-aminopropane hydrochloride [mexiletine HCl]. (Czech.). 1989:94677, 1988, 5 pp. (Slovak), CS250577B1.

14.       D. Hesek   and J. Svetlik. The Convergent Synthesis of [1,3]-Thiazino[2,3-F]-Theophylline and [1,3]-Thiazino[3,2-E]Theophylline Ring-Systems. Synth. Commun., 1988, 18 (11), 1299-1310.

13.       D. Hesek, A. Rybar, F. Povazanec, A. Martvon and J. Kovac. 1,3-Dipolar Cyclo-Addition Reactions of 7-Alkenyl-8-Azidomethylitheophyllines or 7-Alkynyl-8-Azidomethyltheophyllines. Collect. Czech. Chem. Commun., 1988, 53, 319-328.

12.       F. Szemes, M. Tegza, D. Hesek, A. Rybar and E. Zlatinsky. Preparation of 1-(2,6-dimethylphenoxy)-2-propanol as intermediate for pharmaceuticals. (Czech.). 1988:5683, 1987, 4 pp. (Slovak), CS235184B1.

11.       F. Szemes, A. Rybar, D. Hesek, M. Tegza and R. Kosalko. Preparation of 1-(2,6-dimethylphenoxy)-2-propylamine as an antiarrhythmic drug. (Czech.). 1988:492467, 1987, 6 pp. (Slovak), CS239418B1.

10.       J. Nevydal, M. Manduch, K. Siska, R. Frimm, O. Gattnar, D. Hesek   and A. Rybar. Preparation of 1-(2,6-dimethylphenoxy)-2-propanone as an intermediate for pharmaceutics. (Czech.). 1988:528579, 1987, 3 pp. (Slovak), CS245189B1.

9.         L. Jezek, G. Urbankova, J. Gasparik, E. Hudcovicova, R. Nosal, D. Hesek, A. Rybar and Z. Mahrla. Preclinical evaluation of the antiarrhythmic effect and toxicity of mexiletine. Bratisl. Lek. Listy, 1986, 85, 152-159.

8.         L. Janda, Z. Voticky, A. Rybar and D. Hesek  . Ethyl 5-(5-phenyl-2-furyl)tetrazole-1-acetates. CS232343B1, 1986, 8 pp. (Slovak).

7.         D. Hesek, M. Tegza, A. Rybar, F. Szemes, R. Kosalko and A. Martvon. 1-(2,6-Dimethylphenoxy)-2-propanone. (Czech.). 1986:626047, 1986, 4 pp. (Czech).

6.         M. Tegza, D. Hesek, A. Rybar, R. Kosalko and A. Martvon. Preparation of 1-(2',6'-dimethylphenoxy)-2-propylamine. (Japan). 1988:131273, 1986, 3 pp. (Slovak), CS230305B1.

5.         D. Hesek, M. Tegza, A. Rybar, A. Martvon and R. Kosalko. 1-(2',6'-Dimethylphenoxy)-2-propylazide. (Czech.). 1985:220562, 1984, 4 pp. (Slovak).

4.         F. Povazanec, J. Kovac and D. Hesek  . Furan derivatives. 141. Opening of the furan ring in 5-azido-2-furaldehyde. Collect. Czech. Chem. Commun., 1980, 45, 150-154.

3.         F. Povazanec, J. Kovac and D. Hesek  . Furan derivatives. 145. The conversion of 5-nitrofurfuryl derivatives into 5-aminofurfurylidenemalonodinitrile. Collect. Czech. Chem. Commun., 1980, 45, 752-754.

2.         D. Ilavsky, D. Hesek, F. Povazanec and J. Kovac. HMO [Hueckel molecular orbital] prediction of the formation of cyclized products. Collect. Lect. - Int. Symp. Furan Chem., 3rd, 1979 181-185.

1.         F. Povazanec, J. Kovac and D. Hesek  . Furan-Derivatives .139. New Method of Preparation of Alpha-Amino Derivatives of Furan. Collect. Czech. Chem. Commun., 1979, 44, 3301-3307.

 

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