research | reviews

RESEARCH ARTICLES

Renn J.P. & Clark P.L. (2008) A conserved stable core structure in the passenger domain beta-helix of autotransporter virulence proteins. Biopolymers 89, 420-427. [PDF]

Junker M., Schuster C., McDonnell, A.V., Sorg K.E., Finn M.C., Berger, B. & Clark P.L. (2006) The pertactin beta-helix folding mechanism suggests common themes for secretion and folding of autotransporter proteins. Proceedings of the National Academy of Sciences USA 103, 4918-4923. [PDF]

Evans M.S., Ugrinov, K.G., Frese, M. & Clark P.L. (2005) Homogeneous stalled ribosome nascent chain complexes produced in vivo or in vitro. Nature Methods 2, 757-762. [PDF]

Jain M., Evans M.S., King J. & Clark P.L. (2005) Monocolonal antibody epitope mapping describes tailspike beta-helix folding and aggregation intermediates. Journal of Biological Chemistry 280, 23032-23040. [PDF]

Clark P.L. (2004) Protein folding in the cell: Reshaping the folding funnel. Trends in Biochemical Sciences 29: 527-534. [PDF: article] [PDF: cover]

Benton C.B., King, J. & Clark P.L. (2002) Characterization of a trimeric intermediate on the folding pathway of an interdigitated beta-helix structure. Biochemistry 41, 5093-5103. [PDF]

Clark P.L. & King J. (2001) A newly synthesized, ribosome-bound polypeptide chain adopts conformations dissimilar from early in vitro refolding intermediates. Journal of Biological Chemistry 276, 25411-25420. [PDF]

Raso S.W., Clark P.L., Haase-Pettingell C., King J. & Thomas G.J. (2001) Distinct cysteine sulfhydryl environments detected by analysis of Raman S-H markers of Cys->Ser mutant proteins. Journal of Molecular Biology 307, 899-911. [PDF]

Clark P.L., Weston B.F. & Gierasch L.M. (1998) Probing the folding of a b-clam protein using single-tryptophan constructs. Folding & Design 3, 401-412. [PDF]

Clark P.L., Liu Z.P., Rizo J. & Gierasch L.M. (1997) Cavity formation before stable hydrogen bonding in the folding of a beta-clam protein. Nature Structural Biology 4, 883-886. [PDF]

Clark P.L., Liu Z.P., Zhang J. & Gierasch L.M. (1996) Intrinsic tryptophans of CRABPI as probes of structure and folding. Protein Science 5, 1108-1117. [PDF]

REVIEW ARTICLE

Evans M.S., Clarke T.F. & Clark P.L. (2005) Conformations of co-translational folding intermediates. Protein & Peptide Letters 12: 189-195. [PDF]