Corner Aggregation in Biochips

Colloids, Proteins and drug compounds often precipitate at micro-channel corners. The aggregate size is often large (50 microns) and cannot be explained by polarization mechanisms (DLVO and DC-Dielectrophoresis). The group has discovered a long range electro-osmotic and entrainment mechanism due to field leakage that is responsible for this aggregation. Optimum channel design which minimizes aggregation is now being tested.

Representative Publication: [147]