Confocal Raman Microscope

The alpha 300 Confocal Raman microscope combines a highly efficient Raman Spectrometer with a high resolution confocal optical microscope. This gives the confocal Raman microscope the ability to acquire chemical information non-destructively with a resolution down to ~ 200 nm. This enables you to observe and analyza the distribution of different phases within a sample without specialized sample preparation. Because of the confocal setup, it is possible to collect information from the surface and deep inside a transparent sample to obtain a three dimensional information. The microscope offers imaging capabilities as well as the collection of Raman spectra at specific sample areas.

Surface Plasmon/Electrochemistry Apparatus

(Coherent Ar+-pumped Schwarz Electro-Optics Ti:sapphire laser, Coherent dye laser, Stanford Research lock-in amplifier, Photometrics RS9000 CCD camera, Pine Potentiostat, Newport 4' x 8' optical table). This instrument is used to measure surface plasmon resonances, electrochemistry and in-plane resistivity.

Biorad step-scan interferometer based Fourier Transform Infrared Spectrometer with both HgCdTe and DTGS detectors.

Epifluorescent microscope IX-71 (Olympus)

Epifluorescent microscope is used to obtaine brightfield and fluorescence images at magnification 10, 20 and 40x. Microscope is equiped with a two light sources, lamp for brightfield images and X-Cite 120 PC system (Exfo) for fluorophore excitation, two filter sets for wavelength discrimination (FITC (41001, Chroma) and TRITC (41002)), and PhotonMax512 CCD camera for image acquisition.

Ion Trap Mass Spectrometer (LTQ XL – Thermo Fisher Scientific)

The 2D Linear Ion Trap Mass Spectrometer is used to determine the elemental composition of mass limited samples down to a femtogram. The instrument features dual conversion dynode detectors for enhanced sensitivity, and scans a mass range of 15 - 4,000 m/z. Extended MSⁿ performance provides structural elucidation of biomarkers including small peptides and metabolites. Further, advanced software capabilities allow real-time detection and quantitation of processed analytes produced upstream by microfluidic devices coupled to the system.