Recent Publications/Research In Progress

Recent Publications

• B. Bose, S. Zhao, P. Bondo, G. Bondo, F. Cloran, I. Carmichael, R. Stenutz, B. Hertz and A.S. Serianni, Three-Bond C-O-C-C Spin-Coupling Constants in Carbohydrates: Development of a Karplus Relationship, J. Am. Chem. Soc. 1998, 120, 11158-11173.
  
  
• W.S. Hays, D.J. VanderJagt, B. Bose, A.S. Serianni and R.H. Glew, Catalytic Mechanism and Specificity for Hydrolysis and Transglycosylation Reactions of Cytosolic beta-Glucosidase from Guinea Pig Liver, J. Biol. Chem. 1998, 273, 34941-34948.
  
  
• A. S. Serianni, Carbohydrate Structure, Conformation and Reactivity: NMR Studies with Stable Isotopes, in Bioorganic Chemistry: Carbohydrates, S. Hecht, ed., Oxford University Press, 1999.
  
  
• F. Cloran, I. Carmichael and A.S. Serianni, ¹³C-¹H and ¹³C-¹³C Spin-Coupling Behavior in Aldofuranosyl Rings from Density Functional Theory, J. Phys. Chem. 1999, 103A, 3783-3795.
  
  
• H. Junicke, C. Bruhn, R. Kluge, A.S. Serianni and D. Steinborn, Novel Platinum(IV)-Carbohydrate Complexes: Metal Ion Coordination Behavior of Monosaccharides in Organic Solvents, J. Am. Chem. Soc. 1999, 121, 6232-6241.
  
  
• Z. Hricoviniova-Bilikova, M. Hricovini, M. Petrusova, A.S. Serianni and L. Petrus, Stereospecific Molybic Acid-Catalyzed Isomerization of 2-Hexuloses to Branched-Chain Aldoses, Carbohydr. Res. 1999, 319, 38-46.
  
  
• R. Stenutz, M. Shang and A.S. Serianni, Methyl beta-Lactoside (methyl 4-O-beta-D-galactopyranosyl-beta-D-glucopyranoside) Methanol Solvate, Acta Crystal. 1999, C55, 1719-1721.
  
  
• F. Cloran, I. Carmichael and A.S. Serianni, DFT Calculations on Disaccharide Models: Studies of Molecular Geometries and Trans-O-Glycoside ³J_COCH and ³J_COCH Spin-Couplings, J. Am. Chem. Soc. 1999, 121, 9843-9851.
  
  
• F. Cloran, I. Carmichael and A.S. Serianni, ²J_COC Spin-Coupling Constants Across Glycosidic Linkages Exhibit a Valence Bond-Angle Dependence, J. Am. Chem. Soc. 2000, 122, 396-397.
  
  
• H. Junicke, A.S. Serianni and D. Steinborn, Platinum(IV)-Carbohydrate Complexes: Structure Determination Based on ¹H-¹H, ¹³C-¹H and ¹³C-¹³C Spin-Spin Coupling Constants, J. Org. Chem. 2000, 65, 4153-4161.
  
  
• B. Bose-Basu, J. Zajicek, G. Bondo, S. Zhao, M. Kubsch, I. Carmichael, and A.S. Serianni, Deuterium Spin-Lattice Relaxation Times and Quadrupolar Coupling Constants in Isotopically-Labeled Saccharides, J. Magn. Reson. 2000, 144, 207-216.
  
  
• F. Cloran, I. Carmichael and A.S. Serianni, 2-Deoxy-beta-D-erythro-pentofuranosylamine: Quantum Mechanical Calculations of Molecular Structure and NMR Spin-Spin Coupling Constants in Nitrogen-Containing Saccharides, J. Am. Chem. Soc. 2000, 122, 6435-6448.
  

Manuscripts in Press

• F. Cloran, I. Carmichael and A.S. Serianni, 2-Deoxy-beta-D-erythro-pentofuranose: Hydroxymethyl Group Conformation and Substituent Effects on Molecular Structure, Ring Geometry and NMR Spin-Spin Coupling Constants from Quantum Chemical Calculations, J. Am. Chem. Soc. 2001.
  
  
• S. Zhao, L. Petrus and A.S. Serianni, 1-Deoxy-D-Xylulose: A Synthesis Based on Molybdate-Catalyzed Epimerization of Branched-Chain Aldoses, J. Am. Chem. Soc. 2001.
  

Manuscripts Submitted for Publication

Y. Zhu and A.S. Serianni, Acyclic Forms of [1-¹³C]Aldohexoses in Aqueous Solution: Quantitation by ¹³C NMR and Deuterium Isotope Effects on Tautomeric and Conformational Equilibria, J. Am. Chem. Soc..

Manuscripts in Preparation

• R. Stenutz, M. Vercillo, M. Kubsch, S. Zhao and A.S. Serianni, ¹³C-Labeled Gal-Gal and Gal-Glc Disaccharides: Synthesis Using beta- Galactosidase and Analysis of Trans-O-Glycoside ¹³C-¹H and ¹³C-¹³C Spin-Couplings.
  
  
• R. Stenutz, I. Carmichael, G. Widmalm and A.S. Serianni, Hydroxymethyl Group Conformation in Saccharides: Structural Dependencies of ²J_HH, ³J_HH and ¹J_CH Spin-Spin Coupling Constants.
  

Research in Progress

• Y. Zhu, I.Carmichael, and A.S. Serianni, [¹³C]-Labeled 2-Deoxy-2-acetamido-D-hexoses: Experimental and Theoretical Studies of J-Couplings Involving ¹³C.
  
  
• Y. Zhu, I. Carmichael and A.S. Serianni, Theoretical Studies Trans-N-Glycoside ³J_HNCC and ³J_CNCC in Purine and Pyrimidine Nucleosides.
  
  
• R. Stenutz, B. Hertz, I. Carmichael and A.S. Serianni, Hydroxymethyl Group Conformation in Saccharides: An Integrated Analysis of ²J_CH, ²J_CC, ³J_CH and ³J_CC Spin-Couplings in Aldohexopyranosyl Rings.
  
  
• R. Stenutz, Y. Zhu and A.S. Serianni, Trans-O-Glycoside ¹³C-¹³C Spin-Couplings in a Dissymmetrically Triply-¹³C-Labeled alpha,alpha-Trehalose.
  
  
• B. Basu, M. Shang and A.S. Serianni, ¹³C-¹H and ¹³C-¹³C Spin-Coupling Constants in Deoxyaldopyranosyl Rings: Correlations with Couplings in the Deoxyfuranose of DNA.
  
  
• B. Basu and A.S. Serianni, Effect of O-Phosphorylation on ¹³C-¹H and ¹³C-¹³C Spin-Couplings in Carbohydrates: Substitution and Ionization Effects.
  
  
• S. Zhao, P. Bondo and A.S. Serianni, Synthesis of D-[UL-¹³C₆]Galactose and L-[UL-¹³C₆}Galactose from D-[UL-¹³C₆]Glucose.
  
  
• S. Zhao, P. Bondo, J. Zajicek and A.S. Serianni, ¹³C-¹³C Spin-Couplings in Aldopyranosyl Rings Singly Labeled with ¹³C at C2, C3, C4 and C5.
  
  
• J. Kennedy and A.S. Serianni, ¹³C-¹H and ¹³C-¹³C Spin-Coupling Constants in Conformationally Flexible Idopyranosyl Rings.
  
  
• P. Rosner, S. Van Galder and A. S. Serianni, Enzyme-catalyzed Anomerization: Kinetic Studies of Mutarotase with Deoxy- and Fluorosugars.
  
  
• A. S. Serianni, Ab initio Molecular Orbital Calculations on 2-Deoxy-beta-D-glycero-tetrofuranose: Effect of Glycosidation and Exocyclic C-O Torsion Angles on Ring Structure and Conformation.
  
  
• A. S. Serianni, P. Kline and K. Haller, Crystal Structure of 9-beta-D- Erythrofuranosyladenine: Furanose and N-Glycoside Conformation in Nucleosides Lacking an Exocyclic C5' Hydroxymethyl Substituent.
  
  
• W. Stripe, M. Shang and A. S. Serianni, Crystal Structure of Methyl beta-D-Ribofuranoside.
  
  
• B. Basu, M. Shang and A.S. Serianni, Crystal Structures of Methyl 2-deoxy-beta-D-arabino-hexopyranoside and Methyl 2-deoxy-beta-D-ribo-hexopyranoside.
  
  
• U. Stafford and A.S. Serianni, Synthesis of Uniformly 13C-Labeled Glucose in Potatoes under Closed-Chamber Growth Conditions.