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Zhong Liang, MS
Core Manager, Molecular Biology

Associate Professional Specialist

Education
B.S., China Ocean University

Qingdao, P.R. China 1982

M.S., Institute of Tropical Medicine,

Antwerp, Belgium, 1993

Address
W. M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall
University of Notre Dame
Notre Dame, IN 46556

Contact
Phone: (574) 631-4192
Fax: (574) 631-4048
E-mail: Zhong.Liang.16@nd.edu

Honors and Awards

Leuven University Scholarship, 1994-1997

Belgium Red Cross Fellowship, 1993-1994

Research Interests

Mr. Liang manages the molecular biology core of the W. M. Keck Center for Transgene Research.  He is responsible for the design and construction of molecular vectors for the expression of recombinant proteins and for the generation of transgenic and gene modified mice.

Selected Recent Publications

Iwaki T, Malinverno C, Smith D, Xu Z, Liang Z, Ploplis VA, Castellino FJ.  (2010)  The generation and characterization of mice expressing a plasmin-inactivating active site mutation.  J Thromb Haemost. 8:2341-2344.

 

Sheng Z, Liang Z, Geiger JH, Prorok M, Castellino FJ.  (2009)  The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.  Neuropharmacology.   57:127-136.

Wei X, Chen X, Fontanilla C, Zhao L, Liang Z, Dodel R, Hampel H, Farlow M, Du Y. (2007).  C/T conversion alters interleukin 1A promoter function in a human astrocyte cell line.  Life Sci. 27:1152-1156.

Heinrich JE, Pollard M, Wolter WA, Liang Z, Song H, Rosen ED, Suckow MA. (2006).  Vaccination against prostate cancer using a live tissue factor deficient cell line in Lobund-Wistar rats.  Cancer Immunol Immunother. 56:725-730.

Rosen ED, Xu HF, Liang Z, Martin JA, Suckow M, Castellino FJ. (2005).  Generation of gentically-altered mice producing very low levels of coagulation FVII.  Thromb Haemost. 94:493-497.

Lay AJ, Liang Z, Rosen ED, Castellino FJ. (2005).  Mice with severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities.  J Clin Invest. 115:1552-1561.

 

 

 

 

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