Donahue, Deborah L, BS

Associate Professional Specialist
University of Notre Dame

Education
BS, Cornell University, 1996

Address
W. M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall
University of Notre Dame
Notre Dame, IN 46556

Contact
Phone: (574) 631-2318
Fax: (574) 631-4048
E-mail: ddonahu@nd.edu

Honors and Awards

1999 Laboratory Animal Technician, AALAS certification

Areas of Focus

Ms. Donahue is responsible for animal surgeries of the Transgene Center and also interfaces with the university Institutional Animal Care and Use Committee for preparation of protocols for approval.  She also oversees use of some of the very specialized equipment of the center, most notably the mouse ultrasound technology and mouse continuous hemodynamics employing radiotelemetry.

Selected Recent Publications

Castellino FJ, Donahue DL, Navari RM, Ploplis VA, Walsh M.  (2011) An accompanying genetic severe deficiency of tissue fator protects mice with a protein C deficiency from lethal endotoxemia.  Blood.  117:283-289.

Xu H, Noria F, Sandoval-Cooper MJ, Menchen H, Donahue DL, Ploplis VA, Castellino FJ.  (2009)  Severe deficiency of coagulation Factor VII results in spontaneous cardiac fibrosis in mice.  J Pathol.  217:362-371.

Lay AJ, Northway CM, Donahue DL, Castellino FJ.  (2008)  Low levels of tissue factor rescue protein C-associated pregnancy failure in mice.  J Thromb Haemost.   6:1815-7.

Lay AJ, Donahue D, Tsai MJ, Castelllino FJ. (2007).  Acute inflammation is exacerbated in mice genetically predisposed to a severe protein C deficiency.  Blood.  109:1984-1991.

Iwaki T, Donahue DL, Castellino FJ. (2007).  High levels of LDL-cholesterol rescue the neonatal mortality associated with afibrinogenemia in mice.  J Thromb Haemost. 5:624-626.

Ploplis VA, Balsara R, Sandoval-Cooper MJ, Yin ZJ, Batten J, Modi N, Gaduoa D, Donahue DL, Martin JA, Castellino FJ.  (2004).  Enhanced in vitro prolieferation of aortic endothelial cells from PAI-1-/-mice/  J Biol Chem. 279:6143-6151.