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PUBLICATIONS
Kartika,
R.; Gruffi, T. R.; Taylor, R. E. "Concise Enantioselective Total
Synthesis of Neopeltolide Macrolactone Highlighted by Ether Transfer" Org. Lett. 2008, 10, in press.
Taylor,
R. E. "Tedanolide and the Evolution of Polyketide Inhibitors of
Eukaryotic Protein Synthesis" Nat.
Prod. Res. 2008, 25, 854-861. Highlighted on the cover.
Daly,
E., Taylor, R. E "“Entropy and Enthalpy in the Activity of
Tubulin-based Antimitotic Agents” Curr.
Chem. Biol. 2008, in
press.
Kartika,
R.; Frein, J. D.; Taylor, R. E. "Electrophilone-Induced Ether Transfer:
Stereoselective Synthesis of 2,6-Disubstituted-3,4-Dihydropyrans" J. Org. Chem. 2008, 73, 5592-5594.
Huzil,
J. T.; Chik, J. K.; Slysz, G. W.; Freedman, H.; Tuszynski, J.;
Taylor, R. E.; Sackett, D. L.; Schriemer, D. C. “A Unique Mode of
Microtubule Stabilization Induced by Peloruside A” J. Mol. Biol. 2008, 378, 1016-1030.
Young,
J.; Taylor, R. E. “Evolution of Polyketides: Post-PKS Processing in the
Formation of Spiroketals” Nat. Prod.
Rep. 2008, 25, 651-655.
Taylor,
R. E.; Zhao, Z.; Wünsch, S. “Synthetic Efforts Towards Peloruside
A” Comptes Rendus de
l'Académie des Sciences - CHIMIE 2008, in press.
Kartika,
R.; Taylor, R. E. "Electrophile-Induced Ether Transfer:
An Expedient Route to 2-Cyano-tetrahydropyrans" Heterocycles 2007, 74, 447-459.
Kartika,
R.; Taylor, R. E. "Electrophile-Induced Ether Transfer:
Stereoselective Synthesis of 2,4,6-Trisubstituted Tetrahydropyrans" Angew. Chem. Int. Ed. 2007, 46, 6874-6877.
Taylor,
R. E.; Diene, C. R.; Daly, E. M. “46.11 Synthesis of 1,3-Dienes by
Isomerization of Unconjugated Dienes, Allenes, and Alkynes” in Houben-Weyl Science of Synthesis;
V. H. Rawal and S. A. Kozmin, Eds.; G. Thieme Verlag, Stuttgart, 2008, Vol. 46.
Daly,
E. M.; Taylor, R. E. “Recent
Applications of the Nozaki-Hiyama Kishi Reaction in Natural Product
Synthesis” Chemtracts 2007, 20, 1-8.
Tung,
J. C.; Chen, W.; Taylor, R. E.; Fields, S. C.; Dent III, W. H.; Green,
F. R. "Toward the Synthesis of the Cornexistins" Synthesis 2007, 2388-2396.
Kartika, R., Taylor, R. E. “An
Exhaustive Hydrogenation Strategy to Bicyclic Alkaloids” Chemtracts 2006, 19, 385-390.
Melancon,
B. J.; Perl, N. R.; Taylor, R. E. "Competitive Cationic Pathways and
the Asymmetric Synthesis of Aryl-Substituted Cyclopropanes" Org Lett. 2007, 9, 1425-1428.
Liu,
K.; Taylor, R. E.; Kartika, R. "Electrophile-Induced Ether Transfer: A
New Approach to Polyketide Structural Units" Org. Lett. 2006, 8, 5393-5395.
Hines,
J.; Roy, M.; Cheng, H.; Agapakis, C. M.; Taylor, R. E.; Crews, C.
M. “Myriaporone 3/4 SAR Studies Reveal a Novel Pharmacophore Targeting
Eukaryotic Protein Synthesis” Molecular
Biosystems 2006, 2, 371-379. Highlighted on the cover.
Taylor, R. E.; Fleming, K.
N.; Hearn, B. R. "Total Synthesis of Myriaporones 1, 3, and 4" in
Strategies and Tactics in Organic Synthesis" M. Harmata, Ed., Elsevier,
Amsterdam, 2005, pp. 246-268.
Paquette, W.
D.; Taylor,
R. E. "Conformationally-Biased Macrocyclizations" Chemtracts 2005, 18,
584.
Jin, M.; Taylor, R. E.
"The Total Synthesis of (+)-Peloruside A" Org. Lett . 2005,
7, 1303-1305.
Risatti, C. A.; Taylor, R.
E. "Asymmetric Synthesis of Cyclopropanes via Aldehyde Homologation" Angew. Chem. Int. Ed. 2004,
43, 6671-6672.
Suckow, M. A.; Gutierrez,
L. S.; Risatti, C. A.; Wolter, W. R.; Taylor, R. E.; Pollard, M.;
Navarri, R. M.; Castellino, F. J.; Paoni, N. F. “The
Anti-ischemia Agent Ranolazine Promotes the Development of Intestinal
Tumors in APC(Min/+) Mice” Cancer
Lett. 2004, 209, 165-169.
Fleming, K. N.; Taylor, R.
E. "Total Synthesis and Structural Assignment of Myriaporones 1, 3, and
4" Angew. Chem. Int. Ed. 2004,
43, 1728-1730.
Paquette, W. D.; Taylor,
R. E. "Enantioselective Preparation of the C1-C11 Fragment of
Apoptolidin" Org. Lett. 2004,
6, 103.
Taylor, R. E.; Jin, M.
"Towards the Total Synthesis of Peloruside A; Enantioselective
Preparation of the C8-C19 Region" Org.
Lett. 2003, 5, 4959.
Risatti, C. A.; Taylor, R.
E. "Biomimetic Synthesis of Polycyclic Natural Products from
Polyolefinic Precursors" Chemtracts 2004,
17, 83-91.
Taylor, R. E.; Chen, Y.;
Galvin, G. M.; Pabba, P. "Conformation-Activity Relationships in
Polyketide Natural Products: Towards the Biologically Active
Conformation of Epothilone" Organic
and Biomolecular Chemistry 2004, 2, 127.
Taylor, R. E.;
Engelhardt, F. C.; Schmitt, M. J. "Biosynthetic Inspirations:
Cationic Approaches to Cyclopropane Formation" Tetrahedron 2003,
59, 5623-5634.
Vitale-Brown, A. Taylor,
R. E. "Lewis Acid-Induced Epoxide Rerrangement for Complex Molecule
Synthesis" Chemtracts 2003,
16, 254-258.
Taylor, R. E.; Risatti, C.
A.; Engelhardt, F. C.; Schmitt, M. J. "Cyclopropane Structural Units
from Homoaldol Adducts" Org. Lett . 2003,
5, 1377-1379.
Fumihiko
Yoshimura,
Alexey
Rivkin, Ana E. Gabarda, Ting-Chao Chou, Huajin Dong, George Sukenick,
Florence F. Morel, Richard E. Taylor, and Samuel J. Danishefsky
"Synthesis and Conformational Analysis of (E)-9,10-Dehydroepothilone B,
the Most Potent Epothilone Reported to Date: A Suggestive Linkage
Between Observations in the Chemistry and Biology of Epothilones." Angew. Chem. Int. Ed. 2003,
42, 2518-2521.
Yuan, H.;
Junker,
B.;
Helquist, P.; Taylor, R. E. "Synthesis of Anti-Angiogenic Isocoumarins"
Current Organic
Synthesis 2004,
1, 1.
Taylor, R. E.; Chen, Y.;
Beatty, A.; Myles, D. C.; Zhou, Y. "Conformation-activity Relationships
in Polyketide Natural Products. A New Perspective on the Rational
Design of Epothilone Analogues"
J. Am. Chem.
Soc. 2003,
125, 26. This work was
highlighted by a Science Concentrate in Chemical and Engineering
News, a University of Notre Dame Press Release, and a news
story on NPR (WVPE and " " WFYI).
Taylor, R. E.; Ciavarri,
J. P.; Hearn, B. R.; Engelhardt, F. C.; Schmitt, M. J.; Yuan, H.
"Synthetic Methods for Chemical Diversity Inspired by Natural
Products" in Natural Product Chemistry at the Turn of the Century , 2002, (eds. Rahman, Choudary, Khan;
Print Arts, Karachi) p. 89
Taylor, R. E.; Hearn, B.
R.; Ciavarri, J. C. "A Divergent Approach to Tedanolide and
Myriaporone: Completion of the carbon Skeleton of Myriaporone 1."
Org. Lett. 2002, 4, 2953.
Taylor, R. E. "The Organic
Chemist's Newswire" (journal review) Nature
2001, 413, 678-679.
Engelhardt, F. C.;
Schmitt, M. J.; Taylor, R. E. "Kinetically Controlled Cross-Metathesis
Reactions with High E-Selectivities" Org.
Lett. 2001, 3, 2209-2212.
Taylor, R. E.; Chen, Y.
"The Total Synthesis of Epothilone B" Org.
Lett. 2001, 3, 2221-2224.
Taylor, R. E.; Engelhardt,
F. C.; Schmitt, M. J.; Yuan, H. "Synthetic Methods for the Construction
of Structurally Diverse Cyclopropanes"
J. Am. Chem.
Soc. 2001,
123, 2964.
Taylor, R. E.; Schmitt, M.
J.; Yuan, H. "Structural Diversity Based on Cyclopropane Scaffolds" Org. Lett. 2000,
2, 601-603.
Taylor, R. E.; Engelhardt,
F. C.; Yuan, H. "Oligocyclopropanes from Cationic Intermediates" Org. Lett. 1999,
1, 1257-1260.
Taylor, R. E.; Ciavarri,
J. P. "2-Bromoallyl Acetate: A Useful Structural Unit for Sequential
Carbon-Carbon Bond Formation" Org.
Lett. 1999, 1, 467-470.
Taylor, R. E.; Zajicek, J.
"The Conformational Properties of Epothilone" J. Org. Chem. 1999,
64, 7224-7228.
Taylor, R. E.; Ciavarri,
J. C.; Hearn, B. R. "A Divergent Approach to Tedanolide and
Myriaporone: Enantioselective Preparation of the Common
Intermediate" Tetrahedron Lett. 1998,
39, 9361.
Taylor, R. E.; Galvin, G.
M.; Hilfiker, K. A.; Chen, Y. "A Formal Total Synthesis of Epothilone
A: Asymmetric Preparation of the C1-C6 and C7-C12 Fragments" J. Org. Chem. 1998,
63, 9580.
Patterson, S.; Smith, B.
D.; Taylor, R. E. "Tuning the Affinity of a Synthetic Sialic Acid
Receptor Using Combinatorial Chemistry" Tetrahedron Lett. 1998, 39, 3111.
Patterson, S.; Smith, B.
D.; Taylor, R. E. "Fluorescent Sensing of Ribonucleoside
5'-Triphosphate" Tetrahedron Lett. 1997,
38, 6323.
Taylor, R. E.; Ameriks, M.
K.; LaMarche, M. J. "A Novel Approach to Oligocyclopropane Structural
Units" Tetrahedron Lett. 1997,
38, 2057.
Taylor, R.
E.;
Haley,
J.
D. "Towards the Synthesis of Epothilone A. Enantioselective Preparation
of the Thiazole Sidechain and Macrocyclic Ring Closure" Tetrahedron Lett. 1997,
38, 2061.
Publications
with Paul Wender
Wender, P.
A.;
Taylor,
R.
E.; Taxol subgroup "The Pinene Path to Taxanes 5. Stereocontrolled
Synthesis of a Versatile Taxane Precursor" J. Am. Chem. Soc. 1997, 119, 2755.
Wender, P.
A.;
Taylor,
R.
E.; Taxol subgroup "The Pinene Path to Taxanes 6. A Concise Synthesis
of Taxol" J. Am. Chem. Soc. 1997,
119, 2757.
Wender,P.
A.;
Taylor,
R.
E.; Taxol subgroup "The Pinene Path to Taxanes: Genesis and Evolution
of a Synthesis Strategy" ACS Symposium Series 583, Taxane Anticancer
Agents: Basic Science and Current Status Ojima, I.; Georg, G. Ed.
American Chemical Society: Washington D. C., 1995, pp. 326-339.
Publications
with Art Schultz
Schultz, A.
G.;
Taylor,
R.
E. "Diastereoselective Enolate Alkylations. Asymmetric Syntheses of
3-Alkyl-3-carbomethoxy-2-exo-methylene- cyclohex-5-en-1-ones." J. Am. Chem. Soc. 1992,
114, 3937.
Schultz, A.
G.;
Taveras,
A. G.; Taylor, R. E.; Tham, F. S.; Kullnig, R. K. "Solid State
Photochemistry. Remarkable Effects of the Packing of Molecules in
Crystals on the Diastereoselectivity of the Intramolecular 2+2
Photocycloaddition of a 4-(3'-Butenyl) -2,5-cyclohexadien-1-one." J. Am. Chem. Soc. 1992,
114, 8725
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