Regenerative biology is the science of understanding the mechanisms of natural regeneration that are used in the animal world to replace cells, tissues and complex structures and how these mechanisms differ from those that lead to fibrosis, or scarring.
Regenerative medicine is the application of this knowledge to enable the regeneration of biological structures that normally do not regenerate well. The process of regeneration requires a source of regeneration-competent cells, the right systemic and local environmental signals, and the absence of inhibitors of regeneration. There are four basic types of regeneration in multicellular animals: Single cell regeneration, such as neuronal axon re-growth; compensatory hyperplasia of differentiated cells, as seen in liver regeneration; regeneration by reserve adult stem cells, characteristic of a wide variety of issues and organisms; and regeneration via stem cells created by dedifferentiation, a mode used by amphibians to regenerate a wide variety of complex structures. Fibrosis and regeneration have been studied for over two centuries. But only recently, with the discovery that many non-regenerating tissues harbor regeneration-competent cells and that some stem cell populations appear to be developmentally plastic, has the study of regenerative biology and medicine been given major attention. The intent of this workshop is to bring together well-known experts as well as a substantial number of younger investigators on regeneration who are using a wide range of experimental systems to synthesize the current state of our knowledge on the biology of regeneration and to assess our progress toward the establishment of a regenerative medicine. Web site: http://www.biocomplexity.indiana.edu/

Organizers
David L. Stocum, IUPUI, Center for Regenerative Biology and Medicine
James A. Glazier, IUB, Biocomplexity Institute
Anton Neff, IUB, Center for Regenerative Biology and Medicine
Mark Alber, University of Notre Dame, Biocomplexity Center
Funding
Biocomplexity Institute, IUB
College of Arts and Sciences, IUPUI
Interdisciplinary Center for the Study of Biocomplexity, Notre Dame
Program in Medical Sciences, IUB
Confirmed Speakers
Alexander Anderson University of Dundee (angiogenesis theory)
Anthony Mescher, IU (amphibian regeneration)
Anton Neff, IU (amphibian regeneration)
Bakhtier Vasiev, University of Dundee (wound healing)
Bruce Carlson, U. Michigan (muscle regeneration)
Bryon Petersen, U. Florida (stem cell plasticity)
Chetan Gadgil, U. Minnesota (limb development, computation)
David Gardiner, UC Irvine (amphibian regeneration)
Diana Clarke, Curis (stem cell plasticity)
Ed Srour, IUPUI (stem cell plasticity)
Eliezer Shochat, Weizmann Institute (angiogenesis)
Ellen Chernoff, IUPUI (amphibian regeneration)
Ellen Heber-Katz, Wistar, U. Penn (heart regeneration)
Feng Zhou (IUPUI, adult neural stem cells)
George Hentschel, Emory U. (simulation of axonal regeneration)
Hans-Georg Simon, Northwestern U. (amphibian regeneration)
Hiroyuki Ide (Tohoku University, limb regeneration)
Howard Levine, Iowa State (angiogenesis)
Ioannis Yannas, MIT (adult skin and nerve regeneration)
Jo Ann Cameron, U. Illinois (amphibian regeneration)
John Dallon, BYU (wound healing, computation)
Jon Henry, U. of Illinois (amphibian regeneration)
Karen Echeverri (Max Planck, Dresden, stem cell plasticity)
Katia Del-Rio Tsonis, Miami U Ohio (amphibian regeneration)
Katsutoshi Yoshizato (Hiroshima University, skin and liver regeneration)
Ken Muneoka, Tulane University (role of msx in regeneration)
Loren Field, IUPUI (heart regeneration)
Michael King, ISU (amphibian regeneration)
Nadia Malouf-Anderson, N. Carolina (stem cell plasticity)
Panagiotis Tsonis, U. Dayton (amphibian regeneration)
Patrizia Ferretti (University College, London)
Phil Newmark, U. of Illinois (planarian regeneration)
Rosamund Smith, Eli Lilly (amphibian regeneration)
Rosmarie Hunziker, DARPA
Shannon Odelberg, University of Utah (amphibian regeneration)
Simon Rhodes, IUPUI (amphibian regeneration)
Stewart Newman, New York Medical College (limb development)
Teri Belecky-Adams, IUPUI (amphibian regeneration)
Thomas Alcaron, Oxford University (angiogenesis, computation)
W.-S. Kim, Sogang U., Seoul, Korea (amphibian regeneration)